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Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy

Lau, E Sedy, J Sander, C Shaw, M A Feng, Y Scortegagna, M Claps, G Robinson, S Cheng, P Srivas, R ...

Published in Oncogene

The resistance of melanoma to current treatment modalities represents a major obstacle for durable therapeutic response, and thus the elucidation of mechanisms of resistance is urgently needed. The crucial functions of activating transcription factor-2 (ATF2) in the development and therapeutic resistance of melanoma have been previously reported, a...

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