Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy
...Published in Oncogene
The resistance of melanoma to current treatment modalities represents a major obstacle for durable therapeutic response, and thus the elucidation of mechanisms of resistance is urgently needed. The crucial functions of activating transcription factor-2 (ATF2) in the development and therapeutic resistance of melanoma have been previously reported, a...
