Ideker Lab - UC San Diego
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Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic pro...

Mercer, Em Lin, Yc Benner, C Jhunjhunwala, S Dutkowski, J Flores, M Sigvardsson, M Trey Ideker Glass, Ck Murre, C ...

Published in Immunity

Recent studies have documented genome-wide binding patterns of transcriptional regulators and their associated epigenetic marks in hematopoietic cell lineages. In order to determine how epigenetic marks are established and maintained during developmental progression, we have generated long-term cultures of hematopoietic progenitors by enforcing the...

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